Epidemiology of subacute sclerosing panencephalitis (SSPE) and other encephalitides in Karachi area; a progress note.
نویسندگان
چکیده
Relative frequency of neurologic diseases in Karachi, with special reference to inflammatory disorders has been estimated by using the comprehensive data from the Deptt. of Neurology, Dow Medical College, Karachi, The incidence of subacute scierosing pan encephalitis has been estimated to be approx. 10 per million. Figures for multiple sclerosis appear comparable to those from India, Turkey and Israel. Rates for active encephalitides and postencephalitic sequelae are unbelievably higher than in the developed countries (JPMA 36:169 1986).
منابع مشابه
Neurovirological research of encephalitides in and around Karachi. The clinical aspects (interim report).
One hundred-and-fourteen cases of encephal itides and encephalopath ies were selected from the patients admitted to the Neurology ward Civil Hospital, Karachi (CHK), during the twelve years’ period from 1971 to June 1983. There were eleven cases of subacute scierosing pan encephalities (SSPE) and seven cases of chronic progressive encephalopathies (CPE). Forty-three cases of encephalitides and ...
متن کاملMeasles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis.
Studies on the immunoprecipitation of the proteins of several different measles and subacute sclerosing panencephalitis (SSPE) virus strains from lysates of infected cells have revealed a relative lack of antibodies to the nonglycosylated viral membrane protein (M) in the sera of patients with SSPE, in contrast to a high level of antibodies to other viral proteins. No evidence was found for the...
متن کاملSubacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the ...
متن کاملEpidemiology of Subacute Sclerosing Panencephalitis (SSPE) in Germany from 2003 to 2009: A Risk Estimation
Subacute sclerosing panencephalitis (SSPE) is a fatal long-term complication of measles infection. We performed an estimation of the total number of SSPE cases in Germany for the period 2003 to 2009 and calculated the risk of SSPE after an acute measles infection. SSPE cases were collected from the Surveillance Unit for Rare Paediatric Diseases in Germany and the Institute of Virology and Immun...
متن کاملHigh-dose intravenous ribavirin therapy for subacute sclerosing panencephalitis.
Two patients with subacute sclerosing panencephalitis (SSPE) were treated safely and effectively with high doses of intravenous ribavirin combined with intraventricular alpha interferon. The ribavirin concentrations maintained in the serum and cerebrospinal fluid were higher than those which inhibit SSPE virus replication in vitro and in vivo.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 36 7 شماره
صفحات -
تاریخ انتشار 1986